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Philadelphia hasn’t lost a game in September since 2021 and is 3-0 in season openers under coach Nick Sirianni.

The Eagles will try to extend that success in a different hemisphere in Friday night’s unprecedented Week 1 date with the Green Bay Packers in Sao Paulo, Brazil, the first NFL regular-season game in South America.

“It’s going to be good for us to go play in a neutral site and handle the different things that pop up in the NFL,” Sirianni said.

“… There are things you can’t control. What we can control is our effort, we can control our attitude, we can control our core values, and we’re going to focus on that this week.”

Philadelphia won its first eight games and started 13-1 in 2022 en route to advancing to Super Bowl LVII. The Eagles won their first five contests and started 10-1 last season before losing in the wild-card round.

Green Bay is coming off its fourth playoff appearance in five seasons under coach Matt LaFleur. The Packers lost to the San Francisco 49ers on a late Christian McCaffrey touchdown run in the divisional round last season after a wild-card victory over the Dallas Cowboys.

It’s a business trip to Brazil for both teams with no time for sightseeing. The Eagles planned to arrive Wednesday night after a 10-hour flight, hold a walk-through at Corinthians Arena on Thursday, and fly straight back to Philadelphia after Friday night’s game.

“We’re professionals,” Eagles receiver A.J. Brown said. “We’re down there to win a football game. We’re not down there to see the city, do all this other stuff. This is not a vacation. This is a football game.”

The Packers arranged a 10-hour direct flight leaving from Green Bay on Wednesday morning and, as the “visiting” team, they will hold their walk-through Thursday at the Corinthians soccer club’s training ground.

“It’s not going to be anything crazy that we’ve never done before, and I would expect the same from Philly,” LaFleur said. “… I’ve only talked to our guys about the Philadelphia Eagles, and what we need to do.”

The quick turnaround time may be disruptive, but it also gives NFL officials and players who are concerned about security some peace of mind.

“I do not want to go to Brazil,” Eagles cornerback Darius Slay said on his “Big Play Slay” podcast this week. “They already told us not to leave the hotel. They told us we can’t do too much because the crime rate is crazy. NFL, why do you want to send us somewhere where the crime rate is so high?”

A massive mural of starting quarterbacks Jalen Hurts of the Eagles and Jordan Love of the Packers adorns the side of a building in downtown Sao Paulo, but the spotlight in the stadium will be on the running backs.

Saquon Barkley, a two-time Pro Bowl selection, joined Philadelphia after six seasons and more than 5,000 rushing yards with the division-rival New York Giants.

Josh Jacobs, the 2022 NFL rushing leader and also a two-time Pro Bowl pick, signed with Green Bay after five seasons and more than 5,500 rushing yards with the Oakland/Las Vegas Raiders.

“I’m just trying to not let it be me, the guy who messes it up,” Jacobs said. “That’s my biggest thing going into Game 1 is just trying to be very disciplined in my keys, and try to put my little spin on it when I get a chance.”

On the injury front, Eagles linebacker Devin White (ankle) did not participate in practice on Wednesday, and cornerback Isaiah Rodgers (hand) had limited participation.

Rookie running back MarShawn Lloyd (hamstring) did not participate in practice for the Packers on Tuesday. On limited duties were linebacker Edgerrin Cooper (hip), receiver Romeo Doubs (hand), running back Emanuel Wilson (hip), and cornerback Carrington Valentine (hamstring).

–Field Level Media